In a recent episode of Rev Up Health, Dr. Mark and Tandi Hechler welcomed Christina O’Connor RD from Pendulum Therapeutics to discuss the groundbreaking work the company is doing in the field of gut health. Pendulum Therapeutics isn’t your average probiotic company; they’re pioneers in developing targeted probiotics based on rigorous scientific research.

Beyond Traditional Probiotics: A Scientific Approach

Pendulum Therapeutics was founded by a team of PhD scientists with a background in DNA sequencing. They recognized the importance of the gut microbiome and set out to address specific health needs with carefully chosen bacterial strains. Their journey began with the discovery of Akkermansia, a unique strain with significant benefits for gut integrity and metabolic health.

The Akkermansia Advantage

Akkermansia is a key focus for Pendulum. This bacteria, often found in the guts of healthy centenarians, plays a vital role in maintaining a healthy gut lining and has shown promise in managing blood sugar levels. Pendulum’s innovative technology allows them to cultivate and deliver this oxygen-sensitive bacteria in a live and effective form.

Clinical Validation: The Pendulum Difference

What sets Pendulum Therapeutics apart is their commitment to clinical research. Their flagship product, Pendulum Glucose Control, underwent a rigorous double-blind, randomized, placebo-controlled trial, the gold standard for scientific studies. The results demonstrated its effectiveness in lowering A1C levels and reducing post-meal glucose spikes, even outperforming Metformin in some aspects.

Beyond Glucose Control: A Range of Targeted Solutions

Pendulum’s product line extends beyond glucose management. Their GLP-1 probiotic targets insulin resistance and weight management, working to restore the body’s natural metabolic functions. They also offer a polyphenol booster to nourish Akkermansia and support a healthy gut environment.

The Gut-Brain Connection: A New Frontier

Pendulum is at the forefront of exploring the gut-brain axis, the intricate link between the gut microbiome and brain health. Their research suggests that specific probiotic strains can influence mood, cravings, and even mental health conditions. A particularly exciting study is investigating the potential of their Glucose Control formulation in managing bipolar depression.

The Future of Probiotics: Targeted Solutions for Specific Needs

Pendulum Therapeutics envisions a future where probiotics are tailored to individual needs, much like antibiotics target specific infections. Their ongoing research and development of novel strains promise to revolutionize how we approach gut health and overall well-being.

Want to learn more about Pendulum Therapeutics and their innovative approach to gut health?

Listen to the full podcast episode to hear Christina’s insights and discover how Pendulum’s targeted probiotics can help you unlock your health potential.

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